Sunday, 01 March 2015 11:32
Published in IVF Research

Effect of micro-vibration culture system on embryo development

Hur YS1, Park JH, Ryu EK, Park SJ, Lee JH, Lee SH, Yoon J, Yoon SH, Hur CY, Lee WD, Lim JH

1 Department of Anatomy, School of Medicine, Kangwon National University, Chuncheon, 200-701, Korea
* Corresponding author. E-mail address: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

PURPOSE:
Micro-vibration culture system was examined to determine the effects on mouse and human embryo development and possible improvement of clinical outcomes in poor responders.

MATERIALS AND METHODS:
The embryonic development rates and cell numbers of blastocysts were compared between a static culture group (n = 178) and a micro-vibration culture group (n = 181) in mice. The embryonic development rates and clinical results were compared between a static culture group (n = 159 cycles) and a micro-vibration culture group (n = 166 cycles) in poor responders. A micro-vibrator was set at a frequency of 42 Hz, 5 s/60 min duration for mouse and human embryo development.

RESULTS:
The embryonic development rate was significantly improved in the micro-vibration culture group in mice (p < 0.05). The cell numbers of mouse blastocysts were significantly higher in the micro-vibration group than in the static culture group (p < 0.05). In the poor responders, the rate of high grade embryos was not significantly improved in the micro-vibration culture group on day 3. However, the optimal embryonic development rate on day 5 was improved in the micro-vibration group, and the total pregnancy rate and implantation rate were significantly higher in the micro-vibration group than in the static culture group (p < 0.05).

CONCLUSIONS:
Micro-vibration culture methods have a beneficial effect on embryonic development in mouse embryos. In poor responders, the embryo development rate was improved to a limited extent under the micro-vibration culture conditions, but the clinical results were significantly improved.

J Assist Reprod Genet. 2013 Jun;30(6):835-41.

Download:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696450/pdf/10815_2013_Article_7.pdf

Nikola Tesla
If you want to find the secrets of the universe, think in terms of energy, frequency and vibration

Newsletter

Your mail id is very confidential ever.

Contact

SimSoTec GmbH, Am Seeufer 98, 40880 Ratingen info@invitro360.com
 
We use cookies

We use cookies on our website. Some of them are essential for the operation of the site, while others help us to improve this site and the user experience (tracking cookies). You can decide for yourself whether you want to allow cookies or not. Please note that if you reject them, you may not be able to use all the functionalities of the site.