Rethinking In Vitro Embryo Culture: New Developments in Culture Platforms and Potential to Improve Assisted Reproductive Technologies1 Gary D. Smith, Shuichi Takayama, Jason E. Swain 1. Research in the authors' laboratories (G.D.S. and S.T.) on culture platforms have been supported by the National Institutes of Health (NIH; HD 049607), the United States Department of Agriculture (USDA), the Michigan Economic Development Corporation (MEDC; GR 696), the U.S. Army Research Laboratory and the U.S. Army Research Office under contract/grant number DAAD19-03-1-0168, and the Coulter foundation   Biology...

Mechanical agitation during the in vitro culture of human pre-implantation embryos drastically increases the pregnancy rate Evgenia Isachenko 1, Robert Maettner, Vladimir Isachenko, Steffen Roth, Rolf Kreienberg, Karl Sterzik   1. Section of Gynaecological Endocrinology and Reproductive Medicine, University of Ulm, Germany. This email address is being protected from spambots. You need JavaScript enabled to view it.     Clin Lab, 2010;56(11-12):569-76.   Abstract Background: The in vivo developing embryo is naturally exposed to constant vibrations...

Effect of micro-vibration culture system on embryo development   Yong Soo Hur 1, Jeong Hyun Park, Eun Kyung Ryu, Sung Jin Park, Jun Ho Lee, Soo Hee Lee, Jung Yoon, San Hyun Yoon, Chang Young Hur, Won Don Lee, Jin Ho Lim   1. Department of Anatomy, School of Medicine, Kangwon National University, Chuncheon, 200-701, Korea. This email address is being protected from spambots. You need JavaScript enabled to view it.   J Assist Reprod Genet. 2013 Jun;30(6):835-41 Epub: 2013 May 9.   Abstract Purpose: Micro-vibration culture system was examined...

Micro-vibration culture of human embryos improves pregnancy and implantation rates I. El-Danasouri, N.L. Sandi-Monroy, T. Winkle, K. Ott, C. Krebs, D.H.A. Maas, F. Gagsteiger Kinderwunsch-Zentrum Ulm/ Stuttgart, Ulm, BW, Germany * Corresponding author. E-mail address: This email address is being protected from spambots. You need JavaScript enabled to view it.   OBJECTIVE Embryos in vivo are not present in a static condition, since in the fallopian tube they are exposed to continuous movement, compression caused by the cilia and peristaltic movements, and shear stress from tubal...

Micro-Vibration culture and group culture increase fertilization and implantation rates in human embryos   El Danasouri 1, N. Sandi-Monroy, T. Winkle, N. Reeka, F. Gagsteiger       1 Kinderwunschzentrum Ulm, Praxis Dr. Gagsteiger, Ulm, Germany * Corresponding author. E-mail address: This email address is being protected from spambots. You need JavaScript enabled to view it.m   AbstractSeveral studies have shown that culture of human and mice embryos in groups improves embryo development, implantation and clinical pregnancy rates 1,2,3. Paria and Day, 1990 have found...

Comparison of static culture, micro-vibration culture, and micro-vibration culture with co-culture in poor ovarian responders   Yong Soo Hur1, Eun Kyung Ryu1, San Hyun Yoon2, Kyung Sil Lim1, Won Don Lee1, Jin Ho Lim1   1. Maria Fertility Hospital, Seoul, Korea 2. Maria Fertility Research Center, Seoul, Korea.   Corresponding author: Yong Soo Hur. Maria Fertility Hospital, 20 Cheonho-daero, Dongdaemun-gu, Seoul 02586, Korea. Tel: +82-2-2250-5572, Fax: +82-2-2250-5585, This email address is being protected from spambots. You need JavaScript enabled to view it. Received February...

In-vitro culture of human embryos with mechanical micro-vibration increases implantation rates   Vladimir Isachenko 1, Robert Maettner, Karl Sterzik, Erwin Strehler, Rolf Kreinberg, Katharina Hancke, Steffen Roth, Evgenia Isachenko   1. Section of Gynaecological Endocrinology and Reproductive Medicine, University of Ulm, Prittwitzstrasse 43, Ulm, Germany. This email address is being protected from spambots. You need JavaScript enabled to view it.     Reprod Biomed Online 2011 Jun;22(6):536-44. Epub 2011 Feb 13. Abstract The in-vitro...

The effects of chemical and physical factors on mammalian embryo culture and their importance for the practice of assisted human reproduction   Petra L Wale 1, David K Gardner 2   1. School of BioSciences, University of Melbourne, Parkville, Victoria, Australia Melbourne IVF, Melbourne, Victoria, Australia This email address is being protected from spambots. You need JavaScript enabled to view it. 2. School of BioSciences, University of Melbourne, Parkville, Victoria, Australia.     Hum Reprod Update. Jan-Feb 2016;22(1):2-22. doi: 10.1093/humupd/dmv034.Epub...

Ca2+ signaling during mammalian fertilization: requirements, players, and adaptations   Takuya Wakai 1, Veerle Vanderheyden, Rafael A Fissore   1. Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, Massachusetts 01003, USA  Cold Spring Harb Perspect Biol. 2011 Apr 1;3(4):a006767 doi: 10.1101/cshperspect.a006767.   Abstract Changes in the intracellular concentration of calcium ([Ca(2+)](i)) represent a vital signaling mechanism enabling communication among cells and between cells and the environment. The initiation...