Abstract
Several studies have shown that culture of human and mice embryos in groups improves embryo development, implantation and clinical pregnancy rates ^1,2,3. Paria and Day, 1990 have found that mouse embryos cultured singly had inferior development to blastocysts and lower cell numbers per blastocyst compared with those cultured in groups, which show a clear evidence that specific growth factors of embryonic origin participate in preimplantation embryo development and blastocyst functions in an autocrine/paracrine manner. Recently, it has been suggested that micro-vibration increases the cell number of blastocysts in mice ⁴ and have a positive effect on porcine blastocyst development ⁵ and pregnancy and implantation in humans^4,6.

© European Society of Human Reproduction and Embryology.

http://eshre2014.m.tap.cr/catalogs/view/24123

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