Thursday, 26 February 2015 12:37
Published in IVF Research

Micro-Vibration culture and group culture increase fertilization and implantation rates in human embryos

El Danasouri 1, N. Sandi-Monroy, T. Winkle, N. Reeka, F. Gagsteiger

1 Kinderwunschzentrum Ulm, Praxis Dr. Gagsteiger, Ulm, Germany
* Corresponding author. E-mail address: This email address is being protected from spambots. You need JavaScript enabled to view it.


Several studies have shown that culture of human and mice embryos in groups improves embryo development, implantation and clinical pregnancy rates 1,2,3. Paria and Day, 1990 have found that mouse embryos cultured singly had inferior development to blastocysts and lower cell numbers per blastocyst compared with those cultured in groups, which show a clear evidence that specific growth factors of embryonic origin participate in preimplantation embryo development and blastocyst functions in an autocrine/paracrine manner. Recently, it has been suggested that micro-vibration increases the cell number of blastocysts in mice 4 and have a positive effect on porcine blastocyst development 5 and pregnancy and implantation in humans4,6.

© European Society of Human Reproduction and Embryology.


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